911 Transient receptor potential (TRP) channels regulate cell migration of keratinocyte in vitro
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چکیده
منابع مشابه
Transient Receptor Potential (TRP) Channels in the Eye
The first member of transient receptor potential (TRP) channel superfamily was discovered in photoreceptors of Drosophila over 30 years ago.1 Since then this protein superfamily has been extensively characterized based on exponential increases in the number of publications related to TRP channels. With 28 TRP homologous genes identified in mammals, TRP channels have been detected in both neural...
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Cardiac fibrosis is associated with most cardiac diseases. Fibrosis is an accumulation of excessive extracellular matrix proteins (ECM) synthesized by cardiac fibroblasts and myofibroblasts. Fibroblasts are the most prevalent cell type in the heart, comprising 75% of cardiac cells. Myofibroblasts are hardly present in healthy normal heart tissue, but appear abundantly in diseased hearts. Cardia...
متن کاملTransient receptor potential channels regulate myogenic tone of resistance arteries.
Elevation of intravascular pressure causes depolarization and constriction (myogenic tone) of small arteries and arterioles, and this response is a key element in blood flow regulation. However, the nature of pressure-induced depolarization has remained elusive. In the present study, we provide evidence that a transient receptor potential channel (TRPC6) homologue has a major role in this depol...
متن کاملCanonical transient receptor potential 3 channels regulate mitochondrial calcium uptake.
Mitochondrial Ca(2+) homeostasis is fundamental to regulation of mitochondrial membrane potential, ATP production, and cellular Ca(2+) homeostasis. It has been known for decades that isolated mitochondria can take up Ca(2+) from the extramitochondrial solution, but the molecular identity of the Ca(2+) channels involved in this action is largely unknown. Here, we show that a fraction of canonica...
متن کاملRecent Developments in Vascular Endothelial Cell TRP Channels Transient Receptor Potential Channels in Cardiovascular Function and Disease
Sustained elevation in the intracellular Ca concentration via Ca influx, which is activated by a variety of mechanisms, plays a central regulatory role for cardiovascular functions. Recent molecular biological research has disclosed an unexpectedly diverse array of Ca -entry channel molecules involved in this Ca influx. These include more than ten transient receptor potential (TRP) superfamily ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.938